Written by Chanel M. contributed by Kyle J. Norton, All right reserve
Wuyi Cliff Oolong tea, the best of Oolong and one of 3 ingredients of Tava Tea, is a species of Camellia sinensis belonging to the family Theaceae, native the Wuyi Mountain area. Its leaves and leaf buds has been used as tea in Chinese culture and many places in the world, including Wuyi Rock Tea, Tie Guan Yin tea, Taiwan tea and Oolong tea, Iron Goddess of Mercy and other products in Fujian, etc.. Oolong can be bought as green or black tea but it is best known as a black tea in the process of withering under the strong sun and oxidation before curling and twisting.
9. Neuro- egenerative diseases
a. Toxic amyloid oligomers or fibrils
In the evaluation of Alzheimer's and Parkinson's disease targeting toxic amyloid oligomers or fibrils, in the study of "Black tea theaflavins inhibit formation of toxic amyloid-beta and alpha-synuclein fibrils" by Grelle G, Otto A, Lorenz M, Frank RF, Wanker EE, Bieschke J.[9a], researchers found that theaflavins stimulate the assembly of Aβ(amyloid-beta) and αS(alpha-synuclein) into non-toxic, spherical aggregates and suggested that theaflavins might be useful to remove toxic amyloid deposits in Alzheimer's and Parkinson's disease brains.
b. Lipid Membrane Destabilization
In the assesement of Amyloid-β (Aβ) aggregation is a recognized key process in the pathogenesis of Alzheimer's disease (AD), in the study of "Identification of Polyphenolic Compounds and Black Tea Extract as Potent Inhibitors of Lipid Membrane Destabilization by Aβ42 Aggregates" by Gauci AJ, Caruana M, Giese A, Scerri C, Vassallo N.[9b], researchers found that the small-molecule polyphenols and NBB compounds is particularly effective for protection against membrane damage by the Aβ42 oligomers and suggested that polyphenols and NBB compounds have played a critical role of membrane perforation in the neurodegenerative cascade.
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